The discovery that a myoglobin-like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and in vivo; overexpression of neuroglobin ameliorates the recovery from stroke in experimental animals. The mechanism underlying this remarkable effect is still mysterious.
A globin for the brain / Brunori, Maurizio; Vallone, Beatrice. - In: BIOPHYSICAL JOURNAL. - ISSN 0006-3495. - (2007), pp. 42-42. (Intervento presentato al convegno 51st Annual Meeting of the Biophysical-Society tenutosi a Baltimore -MD - USA nel 2007).
A globin for the brain
BRUNORI, Maurizio;VALLONE, Beatrice
2007
Abstract
The discovery that a myoglobin-like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and in vivo; overexpression of neuroglobin ameliorates the recovery from stroke in experimental animals. The mechanism underlying this remarkable effect is still mysterious.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
