Some 2-substituted 3-pyridinolethers were synthesized, with one side chain bearing a carboxylic function; among these there are products having structure analogies with the prostaglandins. The results of hypolipidemic and hypocholesterolemic tests on experimental hyperdyslipidemic animals, as well as those on the inhibition of platelets aggregation and on fibrinolytic activity are reported.
2-Substituted-3-pyridinolethers as hypolipidemic and platelet aggregation inhibiting agents / Desideri, Nicoletta; Manna, Fedele; Stein, Maria Luisa; G., Vairo; F., Del Gaudio; B., Gentile; E., Marmo. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - 40:9(1985), pp. 630-644.
2-Substituted-3-pyridinolethers as hypolipidemic and platelet aggregation inhibiting agents.
DESIDERI, Nicoletta;MANNA, Fedele;STEIN, Maria Luisa;
1985
Abstract
Some 2-substituted 3-pyridinolethers were synthesized, with one side chain bearing a carboxylic function; among these there are products having structure analogies with the prostaglandins. The results of hypolipidemic and hypocholesterolemic tests on experimental hyperdyslipidemic animals, as well as those on the inhibition of platelets aggregation and on fibrinolytic activity are reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
