Details are reported for the synthesis of Se-(1-carboxyethyl)-selenocysteine (1-CESeC), Se-(1-carboxypropyl)-selenocysteine (1-CPSeC) and Se-(2-carboxyethyl)-selenocysteine (2-CESeC). They can be obtained in pure cristalline form with good yield. Some chromatographic properties, useful for their identification, are described. The three aminoacids are good substrates for snake venom L-aminoacid oxidase, giving the corresponding alpha-ketoacids as reaction products.

Oxidative deamination of Se-(1-carboxyethyl)-,Se-(1-carboxypropyl)- and Se-(2-carboxyethyl)-selenocysteine by snake venom L-aminoacid oxidase / Coccia, Raffaella; Blarzino, Carla; C., Foppoli; Cini, Chiara. - In: PHYSIOLOGICAL CHEMISTRY AND PHYSICS AND MEDICAL NMR. - ISSN 0748-6642. - STAMPA. - 20:(1988), pp. 115-122.

Oxidative deamination of Se-(1-carboxyethyl)-,Se-(1-carboxypropyl)- and Se-(2-carboxyethyl)-selenocysteine by snake venom L-aminoacid oxidase.

COCCIA, Raffaella;BLARZINO, Carla;CINI, Chiara
1988

Abstract

Details are reported for the synthesis of Se-(1-carboxyethyl)-selenocysteine (1-CESeC), Se-(1-carboxypropyl)-selenocysteine (1-CPSeC) and Se-(2-carboxyethyl)-selenocysteine (2-CESeC). They can be obtained in pure cristalline form with good yield. Some chromatographic properties, useful for their identification, are described. The three aminoacids are good substrates for snake venom L-aminoacid oxidase, giving the corresponding alpha-ketoacids as reaction products.
1988
analogs /&/ derivatives/chemical synthesis/metabolism, Indicators and Reagents, Kinetics, L-Amino Acid Oxidase, Oxygen Consumption, Selenium; chemical synthesis/metabolism, Selenocysteine, Snake Venoms, Structure-Activity Relationship, Substrate Specificity
01 Pubblicazione su rivista::01a Articolo in rivista
Oxidative deamination of Se-(1-carboxyethyl)-,Se-(1-carboxypropyl)- and Se-(2-carboxyethyl)-selenocysteine by snake venom L-aminoacid oxidase / Coccia, Raffaella; Blarzino, Carla; C., Foppoli; Cini, Chiara. - In: PHYSIOLOGICAL CHEMISTRY AND PHYSICS AND MEDICAL NMR. - ISSN 0748-6642. - STAMPA. - 20:(1988), pp. 115-122.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/466373
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