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The comparative effects of a 10 day estrogen treatment and estrogen independent hyperprolactinemia on nigral and striatal glutamic acid decarboxylase (GAD, EC 4.1.1.15) activity were investigated in male rats. Data obtained show that estrogen treatment decreases GAD activity in substantia nigra, while an increase was observed in conditions of hyperprolactinemia induced by modulation of strio-nigral GABAergic system by estrogens and prolactin is suggested. © 1982.

Comparative effects of estrogens and prolactin on nigral and striatal GAD activity / Nicoletti, Ferdinando; F., Patti; N., Ferrara; P. L., Canonico; G., Giammona; D. F., Condorelli; U., Scapagnini. - In: BRAIN RESEARCH. - ISSN 0006-8993. - 232:1(1982), pp. 238-241.

Comparative effects of estrogens and prolactin on nigral and striatal GAD activity

NICOLETTI, Ferdinando;
1982

Abstract

The comparative effects of a 10 day estrogen treatment and estrogen independent hyperprolactinemia on nigral and striatal glutamic acid decarboxylase (GAD, EC 4.1.1.15) activity were investigated in male rats. Data obtained show that estrogen treatment decreases GAD activity in substantia nigra, while an increase was observed in conditions of hyperprolactinemia induced by modulation of strio-nigral GABAergic system by estrogens and prolactin is suggested. © 1982.
1982
animals; carboxy-lyases; corpus striatum; drug effects/enzymology; estradiol; estrogens; gad activity; glutamate decarboxylase; inbred strains; male; metabolism; pharmacology; prolactin; rats; substantia nigra; sulpiride
01 Pubblicazione su rivista::01a Articolo in rivista
Comparative effects of estrogens and prolactin on nigral and striatal GAD activity / Nicoletti, Ferdinando; F., Patti; N., Ferrara; P. L., Canonico; G., Giammona; D. F., Condorelli; U., Scapagnini. - In: BRAIN RESEARCH. - ISSN 0006-8993. - 232:1(1982), pp. 238-241.
01a Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/465792
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