Lipoperoxidation plays a key role in inducing the production of aflatoxins and their congeners (norsolorinic acid, averufin, averantin, versicolorin A, sterigmatocystin, and O-methyl sterigmatocystin) by different strains of Aspergillus parasiticus and Aspergillus flavus. The stimulating effect was obtained by adding epoxides, hydroperoxides, and carbon tetrachloride to culture media. The presence in the media of a free radical scavenger (cysteamine) was capable of inhibiting the output of aflatoxins and their precursors induced by epoxides, hydroperoxides, and carbon tetrachloride. The stimulating effect of lipoperoxidation would appear to take place before the biosynthesis of norsolorinic acid. © 1989.
Aflatoxin congener biosynthesis induced by lipoperoxidation / Fanelli, Corrado; Fabbri, Anna Adele; Gianfranco, Panfili; Raffaello, Castoria; Chiara De, Luca; Siro, Passi. - In: EXPERIMENTAL MYCOLOGY. - ISSN 0147-5975. - STAMPA. - 13:1(1989), pp. 61-68. [10.1016/0147-5975(89)90008-x]
Aflatoxin congener biosynthesis induced by lipoperoxidation
FANELLI, Corrado;FABBRI, Anna Adele;
1989
Abstract
Lipoperoxidation plays a key role in inducing the production of aflatoxins and their congeners (norsolorinic acid, averufin, averantin, versicolorin A, sterigmatocystin, and O-methyl sterigmatocystin) by different strains of Aspergillus parasiticus and Aspergillus flavus. The stimulating effect was obtained by adding epoxides, hydroperoxides, and carbon tetrachloride to culture media. The presence in the media of a free radical scavenger (cysteamine) was capable of inhibiting the output of aflatoxins and their precursors induced by epoxides, hydroperoxides, and carbon tetrachloride. The stimulating effect of lipoperoxidation would appear to take place before the biosynthesis of norsolorinic acid. © 1989.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
