The addition of tribromo-, tetrabromo- and chloromethanes to cultures of Aspergillus parasiticus strongly stimulated aflatoxin biosynthesis. The presence of phenobarbital in the cultures enhanced this effect. Following the addition of 14CCl 4 to a culture, after 15 d incubation, 8.6% of the total radioactivity was recovered from the mycelium, and 4.7% from the culture filtrate. Some 0.4% of the total radioactivity was found in microsomes, indicating their involvement in CCl 4 activation and biotransformation.
Effect of halomethanes on aflatoxin induction in cultures of Aspergillus parasiticus / S., Passi; Fanelli, Corrado; Fabbri, Anna Adele; E., Finotti; G., Panfili; M., Nazzaro Porro. - In: JOURNAL OF GENERAL MICROBIOLOGY. - ISSN 0022-1287. - STAMPA. - 131:3(1985), pp. 687-691.
Effect of halomethanes on aflatoxin induction in cultures of Aspergillus parasiticus
FANELLI, Corrado;FABBRI, Anna Adele;
1985
Abstract
The addition of tribromo-, tetrabromo- and chloromethanes to cultures of Aspergillus parasiticus strongly stimulated aflatoxin biosynthesis. The presence of phenobarbital in the cultures enhanced this effect. Following the addition of 14CCl 4 to a culture, after 15 d incubation, 8.6% of the total radioactivity was recovered from the mycelium, and 4.7% from the culture filtrate. Some 0.4% of the total radioactivity was found in microsomes, indicating their involvement in CCl 4 activation and biotransformation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
