Carcinosarcoma of the stomach is a rare biphasic tumor that consists of both carcinomatous and sarcomatous components. The common carcinoma component is tubular or papillary adenocarcinoma and the mesenchymal sarcomatous components are variable but may include leiomyosarcoma, rhabdomyosarcoma and osteosarcoma. The aim of this study was to describe the characteristics of gastric carcinosarcoma and to present a review of the available literature. We report a case of carcinosarcoma in a 62-year-old female including the clinical and histopathological features of this tumor. Following ultrasound and computed tomography scans, laparotomy was performed, revealing a large mass, followed by radical surgery. Macroscopically, a polypoid tumor was observed. Microscopically, the tumor was composed of moderately differentiated adenocarcinoma and poorly differentiated sarcoma with a high mitotic index and necrotic areas. At present, the achievement of a definitive diagnosis is dependent on immunohistochemical staining and radical surgery. Thus, more effective diagnostic methods are required to improve patient survival.

Gastric carcinosarcoma: A case report and review of the literature / R., Cirocchi; S., Trastulli; Jacopo, Desiderio; V., Grassi; I., Barillaro; Santoro, Alberto; C., Boselli; N., Avenia; G., Noya; A., De Sol. - In: ONCOLOGY LETTERS. - ISSN 1792-1074. - STAMPA. - 4:1(2012), pp. 53-58. [10.3892/ol.2012.699]

Gastric carcinosarcoma: A case report and review of the literature

Jacopo Desiderio;SANTORO, Alberto;
2012

Abstract

Carcinosarcoma of the stomach is a rare biphasic tumor that consists of both carcinomatous and sarcomatous components. The common carcinoma component is tubular or papillary adenocarcinoma and the mesenchymal sarcomatous components are variable but may include leiomyosarcoma, rhabdomyosarcoma and osteosarcoma. The aim of this study was to describe the characteristics of gastric carcinosarcoma and to present a review of the available literature. We report a case of carcinosarcoma in a 62-year-old female including the clinical and histopathological features of this tumor. Following ultrasound and computed tomography scans, laparotomy was performed, revealing a large mass, followed by radical surgery. Macroscopically, a polypoid tumor was observed. Microscopically, the tumor was composed of moderately differentiated adenocarcinoma and poorly differentiated sarcoma with a high mitotic index and necrotic areas. At present, the achievement of a definitive diagnosis is dependent on immunohistochemical staining and radical surgery. Thus, more effective diagnostic methods are required to improve patient survival.
2012
carcinosarcoma; gastric tumor
01 Pubblicazione su rivista::01a Articolo in rivista
Gastric carcinosarcoma: A case report and review of the literature / R., Cirocchi; S., Trastulli; Jacopo, Desiderio; V., Grassi; I., Barillaro; Santoro, Alberto; C., Boselli; N., Avenia; G., Noya; A., De Sol. - In: ONCOLOGY LETTERS. - ISSN 1792-1074. - STAMPA. - 4:1(2012), pp. 53-58. [10.3892/ol.2012.699]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/463893
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