Obesity, in particular visceral obesity, has strong associations with cardiovascular disease and is related to many factors that are constituents of the metabolic syndrome. Increasing evidence suggests that features of the metabolic syndrome, including visceral obesity, are associated with a low-grade inflammatory state. Indeed, visceral fat is a source of several molecules, such as leptin, adiponectin, tumor necrosis factor-α, and interleukin 6, that are collectively called adipokines. All of them may induce a proinflammatory state and oxidative damage, leading to initiation and progression of atherosclerosis. Reduced-energy diets might represent an effective and healthful approach for long-term weight loss in patients with metabolic syndrome by reducing the underlying inflammatory condition. Copyright © 2004 by Current Science Inc.

Inflammation, insulin resistance, and obesity / Ferroni, Patrizia; Basili, Stefania; A., Falco; G., Davi. - In: CURRENT ATHEROSCLEROSIS REPORTS. - ISSN 1523-3804. - STAMPA. - 6:6(2004), pp. 424-431.

Inflammation, insulin resistance, and obesity

FERRONI, Patrizia;BASILI, Stefania;
2004

Abstract

Obesity, in particular visceral obesity, has strong associations with cardiovascular disease and is related to many factors that are constituents of the metabolic syndrome. Increasing evidence suggests that features of the metabolic syndrome, including visceral obesity, are associated with a low-grade inflammatory state. Indeed, visceral fat is a source of several molecules, such as leptin, adiponectin, tumor necrosis factor-α, and interleukin 6, that are collectively called adipokines. All of them may induce a proinflammatory state and oxidative damage, leading to initiation and progression of atherosclerosis. Reduced-energy diets might represent an effective and healthful approach for long-term weight loss in patients with metabolic syndrome by reducing the underlying inflammatory condition. Copyright © 2004 by Current Science Inc.
2004
inflammation; insulin resistance; obesity
01 Pubblicazione su rivista::01a Articolo in rivista
Inflammation, insulin resistance, and obesity / Ferroni, Patrizia; Basili, Stefania; A., Falco; G., Davi. - In: CURRENT ATHEROSCLEROSIS REPORTS. - ISSN 1523-3804. - STAMPA. - 6:6(2004), pp. 424-431.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/463590
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