D-Thiazolidine-4-carboxylic acid is a good substrate for hog kidney D-aminoacid oxidase. Data are presented showing that the only oxidation product is delta 3-thiazoline-4-carboxylic acid, which does not undergo further spontaneous degradation. Thus, the oxidation of D-thiazolidine-4-carboxylic acid by D-aminoacid oxidase differs considerably from the oxidation of its L-isomer catalyzed by rat liver mitochondria which gives as final product N-formylcystine, possibly through the intermediate delta 2-thiazoline-4-carboxylic acid.
Oxidation of D-thiazolidine-4-carboxylic acid by hog kidney D-aminoacid oxidase / Coccia, Raffaella; Blarzino, Carla; C., Foppoli; Cini, Chiara. - In: ITALIAN JOURNAL OF BIOCHEMISTRY. - ISSN 0021-2938. - STAMPA. - 28:(1979), pp. 252-260.
Oxidation of D-thiazolidine-4-carboxylic acid by hog kidney D-aminoacid oxidase.
COCCIA, Raffaella;BLARZINO, Carla;CINI, Chiara
1979
Abstract
D-Thiazolidine-4-carboxylic acid is a good substrate for hog kidney D-aminoacid oxidase. Data are presented showing that the only oxidation product is delta 3-thiazoline-4-carboxylic acid, which does not undergo further spontaneous degradation. Thus, the oxidation of D-thiazolidine-4-carboxylic acid by D-aminoacid oxidase differs considerably from the oxidation of its L-isomer catalyzed by rat liver mitochondria which gives as final product N-formylcystine, possibly through the intermediate delta 2-thiazoline-4-carboxylic acid.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
