Thialysine resistant CHO cells utilize thialysine added to the culture medium to a lesser extent than the parental cells. Thialysine is utilized in protein synthesis and it is incorporated into proteins in place of lysine. The parental strain substitutes up to 11% of protein lysine by thialysine, while variant cells substitute a maximum of 5% of protein lysine.

THIALYSINE UTILIZATION BY THIALYSINE RESISTANT CHO CELLS / A. D., Girolamo; M. D., Girolamo; Cini, Chiara; Coccia, Raffaella; C. D., Marco. - In: PHYSIOLOGICAL CHEMISTRY AND PHYSICS AND MEDICAL NMR. - ISSN 0748-6642. - STAMPA. - 18:1(1986), pp. 33-36.

THIALYSINE UTILIZATION BY THIALYSINE RESISTANT CHO CELLS

CINI, Chiara;COCCIA, Raffaella;
1986

Abstract

Thialysine resistant CHO cells utilize thialysine added to the culture medium to a lesser extent than the parental cells. Thialysine is utilized in protein synthesis and it is incorporated into proteins in place of lysine. The parental strain substitutes up to 11% of protein lysine by thialysine, while variant cells substitute a maximum of 5% of protein lysine.
1986
amino acids; analogs /&/ derivatives/metabolism/pharmacology; analysis; animals; cell line; cricetinae; cricetulus; cysteine; drug resistance; protein biosynthesis
01 Pubblicazione su rivista::01a Articolo in rivista
THIALYSINE UTILIZATION BY THIALYSINE RESISTANT CHO CELLS / A. D., Girolamo; M. D., Girolamo; Cini, Chiara; Coccia, Raffaella; C. D., Marco. - In: PHYSIOLOGICAL CHEMISTRY AND PHYSICS AND MEDICAL NMR. - ISSN 0748-6642. - STAMPA. - 18:1(1986), pp. 33-36.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/460379
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