Thialysine resistant CHO cells utilize thialysine added to the culture medium to a lesser extent than the parental cells. Thialysine is utilized in protein synthesis and it is incorporated into proteins in place of lysine. The parental strain substitutes up to 11% of protein lysine by thialysine, while variant cells substitute a maximum of 5% of protein lysine.
THIALYSINE UTILIZATION BY THIALYSINE RESISTANT CHO CELLS / A. D., Girolamo; M. D., Girolamo; Cini, Chiara; Coccia, Raffaella; C. D., Marco. - In: PHYSIOLOGICAL CHEMISTRY AND PHYSICS AND MEDICAL NMR. - ISSN 0748-6642. - STAMPA. - 18:1(1986), pp. 33-36.
THIALYSINE UTILIZATION BY THIALYSINE RESISTANT CHO CELLS
CINI, Chiara;COCCIA, Raffaella;
1986
Abstract
Thialysine resistant CHO cells utilize thialysine added to the culture medium to a lesser extent than the parental cells. Thialysine is utilized in protein synthesis and it is incorporated into proteins in place of lysine. The parental strain substitutes up to 11% of protein lysine by thialysine, while variant cells substitute a maximum of 5% of protein lysine.File allegati a questo prodotto
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