The invention relates to an in vitro method for detecting the activation of NADPH oxidase by measuring gp91phox protein levels in biological fluids, as a marker of oxidative stress. The method is useful for testing the oxidative stress levels in dysmetabolic pathologies, such as diabetes, hypercholesterolemia and hyperlipidemia, in pathologies of the cardiovascular district, such as hypertension, atherosclerosis, cardiac hypertrophy and stroke, and in clinical conditions comprising sepsis and diseases with a strong inflammatory component.
IN VITRO METHOD FOR DETECTING GP91PHOX AS A MARKER OF OXIDATIVE STRESS / Violi, Francesco; Pignatelli, Pasquale. - (2012).
IN VITRO METHOD FOR DETECTING GP91PHOX AS A MARKER OF OXIDATIVE STRESS
VIOLI, Francesco;PIGNATELLI, Pasquale
2012
Abstract
The invention relates to an in vitro method for detecting the activation of NADPH oxidase by measuring gp91phox protein levels in biological fluids, as a marker of oxidative stress. The method is useful for testing the oxidative stress levels in dysmetabolic pathologies, such as diabetes, hypercholesterolemia and hyperlipidemia, in pathologies of the cardiovascular district, such as hypertension, atherosclerosis, cardiac hypertrophy and stroke, and in clinical conditions comprising sepsis and diseases with a strong inflammatory component.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
