This series consists of 25 patients affected with nasopharyngeal carcinoma in an advanced stage (T3-T4) treated at the Radiation Oncology department of the Institute of Radiology, University "La Sapienza", Rome, from 1978 through 1988. The patients were irradiated with X-rays produced by a LinAc with 4 MeV energy, for a total dose of 60/75 Gy on tumor and 50/60 Gy on nodes. In 7 cases radiation therapy was combined with chemotherapy. Actuarial survival at 60 months was 47%; patients with T3 cancer treated with a total tumor dose over 65 Gy showed a significant statistical increase of survival. Adjuvant chemotherapy did not produce statistically significant increase of survival. Radiation therapy was the treatment of choice in nasopharyngeal carcinoma in an advanced stage, whereas the role of chemotherapy remains questionable, even though a bad prognosis requires aggressive and combined treatment.

[Radiotherapy in the treatment of tumors of the nasopharynx in advanced stage] / Donato, Vittorio; MAURIZI ENRICI, Riccardo; E., Banelli; M., Cerqua; Osti, Mattia Falchetto; M., Santarelli; A., Vitturini. - In: LA RADIOLOGIA MEDICA. - ISSN 0033-8362. - STAMPA. - 80:4(1990), pp. 506-509.

[Radiotherapy in the treatment of tumors of the nasopharynx in advanced stage].

DONATO, Vittorio;MAURIZI ENRICI, Riccardo;OSTI, Mattia Falchetto;
1990

Abstract

This series consists of 25 patients affected with nasopharyngeal carcinoma in an advanced stage (T3-T4) treated at the Radiation Oncology department of the Institute of Radiology, University "La Sapienza", Rome, from 1978 through 1988. The patients were irradiated with X-rays produced by a LinAc with 4 MeV energy, for a total dose of 60/75 Gy on tumor and 50/60 Gy on nodes. In 7 cases radiation therapy was combined with chemotherapy. Actuarial survival at 60 months was 47%; patients with T3 cancer treated with a total tumor dose over 65 Gy showed a significant statistical increase of survival. Adjuvant chemotherapy did not produce statistically significant increase of survival. Radiation therapy was the treatment of choice in nasopharyngeal carcinoma in an advanced stage, whereas the role of chemotherapy remains questionable, even though a bad prognosis requires aggressive and combined treatment.
1990
adenocarcinoma; adult; aged; carcinoma; female; humans; male; middle aged; mortality/pathology/radiotherapy; nasopharyngeal neoplasms; neoplasm staging; retrospective studies; squamous cell; survival rate
01 Pubblicazione su rivista::01a Articolo in rivista
[Radiotherapy in the treatment of tumors of the nasopharynx in advanced stage] / Donato, Vittorio; MAURIZI ENRICI, Riccardo; E., Banelli; M., Cerqua; Osti, Mattia Falchetto; M., Santarelli; A., Vitturini. - In: LA RADIOLOGIA MEDICA. - ISSN 0033-8362. - STAMPA. - 80:4(1990), pp. 506-509.
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/458287
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 3
  • ???jsp.display-item.citation.isi??? ND
social impact