Non-small-cell lung cancer remains the leading cause of cancer-related mortality in the United States and Europe. Most patients are diagnosed with metastatic disease for which chemotherapy remains the cornerstone of treatment. In non-metastatic disease, surgery is the most potentially curative therapeutic option, but its outcome is still poor, in particular for patients with lymph node involvement. Therefore, several randomized adjuvant/neoadjuvant trials using chemotherapy and/or radiotherapy investigated the possibility of increasing the overall survival of patients with surgically treated lung cancer. The findings are reviewed in this article.

The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology / Passaro, Antonio; Trenta, Patrizia; Davide, Conte; Giuseppe, Campenni; DE BENEDETTO, Angelina; Cortesi, Enrico. - In: THORACIC SURGERY CLINICS. - ISSN 1547-4127. - 22:2(2012), pp. 243-249. [10.1016/j.thorsurg.2011.11.002]

The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology

PASSARO, ANTONIO;TRENTA, PATRIZIA;DE BENEDETTO, Angelina;CORTESI, Enrico
2012

Abstract

Non-small-cell lung cancer remains the leading cause of cancer-related mortality in the United States and Europe. Most patients are diagnosed with metastatic disease for which chemotherapy remains the cornerstone of treatment. In non-metastatic disease, surgery is the most potentially curative therapeutic option, but its outcome is still poor, in particular for patients with lymph node involvement. Therefore, several randomized adjuvant/neoadjuvant trials using chemotherapy and/or radiotherapy investigated the possibility of increasing the overall survival of patients with surgically treated lung cancer. The findings are reviewed in this article.
2012
lymph node; non-small cell lung cancer; neoadjuvant chemotherapy; adjuvant chemotherapy
01 Pubblicazione su rivista::01a Articolo in rivista
The Impact of Chemotherapy on the Lymphatic System in Thoracic Oncology / Passaro, Antonio; Trenta, Patrizia; Davide, Conte; Giuseppe, Campenni; DE BENEDETTO, Angelina; Cortesi, Enrico. - In: THORACIC SURGERY CLINICS. - ISSN 1547-4127. - 22:2(2012), pp. 243-249. [10.1016/j.thorsurg.2011.11.002]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/457191
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