Our data now show that even in the case of chronic low-energy irradiation, the cells accumulate a large amount of damage which is subsequently repaired in G2. The high efficiency of repair in G2 is confirmed by the fact that, if it is obstructed, it is possible to detect even slight damage which would otherwise be very difficult to demonstrate. Our experiments also showed a tendency for the mitotic index to increase at the same time as repair failure occurred in G2.
Studies on chromosomes aberrations induced by incorporated tritium: Effect of post-treatment with hydroxyurea and caffeine in G2 / Pelliccia, Franca; Belloni, Giorgio; Bosi, Alba; Micheli, Aldo; Olivieri, Gregorio. - In: MUTATION RESEARCH. - ISSN 0027-5107. - STAMPA. - 199:(1988), pp. 139-144. [10.1016/0027-5107(88)90239-4]
Studies on chromosomes aberrations induced by incorporated tritium: Effect of post-treatment with hydroxyurea and caffeine in G2.
PELLICCIA, Franca;BELLONI, Giorgio;BOSI, Alba;MICHELI, Aldo;OLIVIERI, Gregorio
1988
Abstract
Our data now show that even in the case of chronic low-energy irradiation, the cells accumulate a large amount of damage which is subsequently repaired in G2. The high efficiency of repair in G2 is confirmed by the fact that, if it is obstructed, it is possible to detect even slight damage which would otherwise be very difficult to demonstrate. Our experiments also showed a tendency for the mitotic index to increase at the same time as repair failure occurred in G2.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
