DAPI, a compound specific for the AT bases of DNA, causes gaps and breaks in three human chromosome sites, at the 1q41-1q42 interface, 2q31, and 7p22. It also induces undercondensation of a chromosome site at the 13q21-13q22 interface. The first three sites have the characteristics of 'common fragile sites' and are present as gaps and breaks on the chromosomes of seven individuals.
DAPI-INDUCIBLE COMMON FRAGILE SITES / Pelliccia, Franca; Rocchi, Angela. - In: CYTOGENETICS AND CELL GENETICS. - ISSN 0301-0171. - STAMPA. - 42:3(1986), pp. 174-176. [10.1159/000132272]
DAPI-INDUCIBLE COMMON FRAGILE SITES
PELLICCIA, Franca;ROCCHI, Angela
1986
Abstract
DAPI, a compound specific for the AT bases of DNA, causes gaps and breaks in three human chromosome sites, at the 1q41-1q42 interface, 2q31, and 7p22. It also induces undercondensation of a chromosome site at the 13q21-13q22 interface. The first three sites have the characteristics of 'common fragile sites' and are present as gaps and breaks on the chromosomes of seven individuals.File allegati a questo prodotto
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