Abstract Rationale. The forced-swimming test (FST) is utilized to reproduce passive coping responses to stress that may model a relevant aspect of human depression in rodent species. Animals showing high levels of passive responses to the FST are assumed to model pathologically depressed individuals. Objectives. We evaluated sensitivity of FST- induced behavioral responses to the interaction between genetic and environmental influences. Methods. Behavioral responses to FST were evaluated in naive mice of the ...
Genotype-and experience-dependent susceptibility to depressive-like responses in the forced-swimming test / Antonio, Alcaro; Cabib, Simona; Ventura, Rossella; PUGLISI ALLEGRA, Stefano. - In: PSYCHOPHARMACOLOGY. - ISSN 0033-3158. - STAMPA. - 164:(2002), pp. 138-143.
Genotype-and experience-dependent susceptibility to depressive-like responses in the forced-swimming test
CABIB, Simona;VENTURA, Rossella;PUGLISI ALLEGRA, Stefano
2002
Abstract
Abstract Rationale. The forced-swimming test (FST) is utilized to reproduce passive coping responses to stress that may model a relevant aspect of human depression in rodent species. Animals showing high levels of passive responses to the FST are assumed to model pathologically depressed individuals. Objectives. We evaluated sensitivity of FST- induced behavioral responses to the interaction between genetic and environmental influences. Methods. Behavioral responses to FST were evaluated in naive mice of the ...I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
