We report here a case of a woman with a cutaneous large B-cell lymphoma of the legs. She had a plaque lesion, superficially ulcerated and necrotized with tumorous borders situated on the posterior side of the right leg and two red or bluish-red nodular lesions. A skin biopsy from both nodular and plaque lesion showed a diffuse infiltrate of atypical large B cells CD20 + and CD79a +, spanning epidermis, dermis and subcutaneous tissue. A therapeutic approach containing anti-CD20 monoclonal antibody (rituximab) was suggested. © M. Carlesimo et al., 2012.
A case of cutaneous large B-cell lymphoma of the legs appearing as chronic venous ulceration / Carlesimo, Marta; Orsini, Diego; Narcisi, Alessandra; Abruzzese, Claudia; Cortesi, Giorgia; DE MARCO, Gabriella; Rossi, Alfredo. - In: HEMATOLOGY REPORTS. - ISSN 2038-8322. - STAMPA. - 4:2(2012), pp. 17-18. [10.4081/hr.2012.e6]