We report here a case of a woman with a cutaneous large B-cell lymphoma of the legs. She had a plaque lesion, superficially ulcerated and necrotized with tumorous borders situated on the posterior side of the right leg and two red or bluish-red nodular lesions. A skin biopsy from both nodular and plaque lesion showed a diffuse infiltrate of atypical large B cells CD20 + and CD79a +, spanning epidermis, dermis and subcutaneous tissue. A therapeutic approach containing anti-CD20 monoclonal antibody (rituximab) was suggested. © M. Carlesimo et al., 2012.
A case of cutaneous large B-cell lymphoma of the legs appearing as chronic venous ulceration / Carlesimo, M., Orsini, D., Narcisi, A., Abruzzese, C., Cortesi, G., DE MARCO, G., Rossi, A.. - In: HEMATOLOGY REPORTS. - ISSN 2038-8322. - STAMPA. - 4:2(2012), pp. 17-18. [10.4081/hr.2012.e6]
A case of cutaneous large B-cell lymphoma of the legs appearing as chronic venous ulceration.
CARLESIMO, Marta;orsini, diego;NARCISI, ALESSANDRA;ABRUZZESE, CLAUDIA;CORTESI, GIORGIA;DE MARCO, Gabriella;ROSSI, Alfredo
2012
Abstract
We report here a case of a woman with a cutaneous large B-cell lymphoma of the legs. She had a plaque lesion, superficially ulcerated and necrotized with tumorous borders situated on the posterior side of the right leg and two red or bluish-red nodular lesions. A skin biopsy from both nodular and plaque lesion showed a diffuse infiltrate of atypical large B cells CD20 + and CD79a +, spanning epidermis, dermis and subcutaneous tissue. A therapeutic approach containing anti-CD20 monoclonal antibody (rituximab) was suggested. © M. Carlesimo et al., 2012.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
