Hematologic malignancies can be associated to dermatological manifestations, with two possible etiopathogenetic mechanisms: a direct invasion of skin by neoplastic cells or a paraneoplastic phenomenon. The eosinophilic dermatosis can be included in the latter class and are a group of polymorphous dermatitis, clinically characterized by papules, plaques, nodules or vescico-bullous lesions, mainly involving sun-exposure sites. Clinical pictures are similar to an insect bite reaction, but in most cases the patients deny any arthropod contacts. Therefore, they are now considered as a hypersensitive reaction to different stimuli induced by lymphoproliferative malignancies and the associated immune-deficient state. Herein, we describe two cases of patients affected by a non-Hodgkin lymphoma (NHL), in whom a diagnosis of insect bite-like reaction (IBLR) was made.
EOSINOPHILIC DERMATOSIS ASSOCIATED WITH HAEMATOLOGICAL MALIGNANCIES: A REPORT OF TWO CASES / Carlesimo, Marta; Narcisi, Alessandra; D., Orsini; C., Abruzzese; P. P., Di Russo; G., La Verde; M. C., Cox. - In: EUROPEAN JOURNAL OF INFLAMMATION. - ISSN 1721-727X. - 10:2(2012), pp. 247-250.
EOSINOPHILIC DERMATOSIS ASSOCIATED WITH HAEMATOLOGICAL MALIGNANCIES: A REPORT OF TWO CASES
CARLESIMO, Marta;NARCISI, ALESSANDRA;D. Orsini;
2012
Abstract
Hematologic malignancies can be associated to dermatological manifestations, with two possible etiopathogenetic mechanisms: a direct invasion of skin by neoplastic cells or a paraneoplastic phenomenon. The eosinophilic dermatosis can be included in the latter class and are a group of polymorphous dermatitis, clinically characterized by papules, plaques, nodules or vescico-bullous lesions, mainly involving sun-exposure sites. Clinical pictures are similar to an insect bite reaction, but in most cases the patients deny any arthropod contacts. Therefore, they are now considered as a hypersensitive reaction to different stimuli induced by lymphoproliferative malignancies and the associated immune-deficient state. Herein, we describe two cases of patients affected by a non-Hodgkin lymphoma (NHL), in whom a diagnosis of insect bite-like reaction (IBLR) was made.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.