Abstract The fatty acid composition of biliary phosphatidylcholine was analyzed in 13 patients with radiolucent gallstones undergoing elective cholecystectomy, and in 11 normolipemic patients without gallstone undergoing abdominal surgery. The only difference in the percentage fatty acid composition between the two groups was a significantly (p less than 0.05) higher percentage arachidonic acid in the first group. This acid was exclusively located in the sn-2 position of phosphatidylcholine (PC), accounting for 13.0 +/- 4.9% in the first group and 8.2 +/- 4.9% in the second (p less than 0.05). The percentage arachidonic acid of PC was negatively correlated (p less than 0.001) with the percentage biliary chenodeoxycholate in gallstone patients, but not in controls. Explanation of these findings is, at present, only speculative.
Structure of biliary phosphatidylcholine in cholesterol gallstone patients / Cantafora, A; Angelico, Mario; Di Biase, A; Pièche, U; Bracci, F; Attili, Adolfo Francesco; Capocaccia, Livio. - In: LIPIDS. - ISSN 0024-4201. - STAMPA. - 16:8(1981), pp. 589-592.
Structure of biliary phosphatidylcholine in cholesterol gallstone patients.
ANGELICO, Mario;ATTILI, Adolfo Francesco;CAPOCACCIA, Livio
1981
Abstract
Abstract The fatty acid composition of biliary phosphatidylcholine was analyzed in 13 patients with radiolucent gallstones undergoing elective cholecystectomy, and in 11 normolipemic patients without gallstone undergoing abdominal surgery. The only difference in the percentage fatty acid composition between the two groups was a significantly (p less than 0.05) higher percentage arachidonic acid in the first group. This acid was exclusively located in the sn-2 position of phosphatidylcholine (PC), accounting for 13.0 +/- 4.9% in the first group and 8.2 +/- 4.9% in the second (p less than 0.05). The percentage arachidonic acid of PC was negatively correlated (p less than 0.001) with the percentage biliary chenodeoxycholate in gallstone patients, but not in controls. Explanation of these findings is, at present, only speculative.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
