We have recently described that in the erythrocytes from uremic patients on chronic hemodialysis, the pentose-phosphate shunt is defective, the membrane concentrations of malonyldialdehyde, resulting from peroxidation of polyunsaturated fatty acids in the membranes themselves, are increased, and the concentrations of vitamin E, an antioxidizing agent, are reduced. In the present study we have analyzed these same metabolic aspects in a group of uremic patients in continuous ambulatory peritoneal dialysis. We have found normal function of the pentose-phosphate shunt, slightly elevated concentrations of malonyldialdehyde compared to controls, but definitely lower than in chronic hemodialysis patients, and higher tocopherol concentrations than in both controls and chronic hemodialysis patients.
Red blood cell membrane lipid peroxidation in continuous ambulatory peritoneal dialysis patients / Taccone Gallucci, M; Giardini, O; Lubrano, Riccardo; Mazzarella, V; Bandino, D; Khashan, S; Mannarino, O; Elli, M; Cozzari, M; Buoncristiani, U; Casciani, Cu. - In: AMERICAN JOURNAL OF NEPHROLOGY. - ISSN 0250-8095. - STAMPA. - 6(1986), pp. 92-95. [10.1159/000167061]
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Titolo: | Red blood cell membrane lipid peroxidation in continuous ambulatory peritoneal dialysis patients | |
Autori: | ||
Data di pubblicazione: | 1986 | |
Rivista: | ||
Citazione: | Red blood cell membrane lipid peroxidation in continuous ambulatory peritoneal dialysis patients / Taccone Gallucci, M; Giardini, O; Lubrano, Riccardo; Mazzarella, V; Bandino, D; Khashan, S; Mannarino, O; Elli, M; Cozzari, M; Buoncristiani, U; Casciani, Cu. - In: AMERICAN JOURNAL OF NEPHROLOGY. - ISSN 0250-8095. - STAMPA. - 6(1986), pp. 92-95. [10.1159/000167061] | |
Handle: | http://hdl.handle.net/11573/454397 | |
Appartiene alla tipologia: | 01a Articolo in rivista |