Benign polyps of the stomach undergo malignant transformation at a rate correlating to the histological type and size of the proliferative lesion. We report a case of a 50-year-old Caucasian woman, affected by a diffuse gastric polyposis of both hyperplastic and adenomatous type. At endoscopy polyps were more than 1,000, scattered over the entire gastric cavity. The patient underwent total gastrectomy. The perilesional gastric mucosa was characterized by the presence of either atrophic or metaplastic areas and by a mild dysplasia. A single tubulo-villous adenomatous polyp was also present in the ascending tract of the colon. The absence of both high-grade dysplastic lesions and outbreaks of neoplastic transformation well correlated with the histochemical and molecular features, confirming the highly proliferative pattern of the polyps in the lack of signs of malignant progression.

Evaluation of the oncogenic risk of diffuse gastric polyposis. A case report / Spaziani, Erasmo; Marcello, Picchio; DI FILIPPO, Annalisa Romina; Narilli, Piero; Pacini, Luca; Moretti, Valentina; Pierino, Lucarelli; DE ANGELIS, Francesco; Ragona, Giuseppe; Petrozza, Vincenzo. - In: REVISTA ESPAÑOLA DE ENFERMEDADES DIGESTIVAS. - ISSN 1130-0108. - STAMPA. - 104:9(2012), pp. 493-496. [10.4321/s1130-01082012000900009]

Evaluation of the oncogenic risk of diffuse gastric polyposis. A case report

SPAZIANI, Erasmo;DI FILIPPO, Annalisa Romina;NARILLI, Piero;PACINI, LUCA;MORETTI, VALENTINA;DE ANGELIS, FRANCESCO;RAGONA, Giuseppe;PETROZZA, Vincenzo
2012

Abstract

Benign polyps of the stomach undergo malignant transformation at a rate correlating to the histological type and size of the proliferative lesion. We report a case of a 50-year-old Caucasian woman, affected by a diffuse gastric polyposis of both hyperplastic and adenomatous type. At endoscopy polyps were more than 1,000, scattered over the entire gastric cavity. The patient underwent total gastrectomy. The perilesional gastric mucosa was characterized by the presence of either atrophic or metaplastic areas and by a mild dysplasia. A single tubulo-villous adenomatous polyp was also present in the ascending tract of the colon. The absence of both high-grade dysplastic lesions and outbreaks of neoplastic transformation well correlated with the histochemical and molecular features, confirming the highly proliferative pattern of the polyps in the lack of signs of malignant progression.
2012
adenomatous polyps; malignant potential; hyperplastic polyps; immunohistochemistry; molecular assay; diffuse gastric polyposis
01 Pubblicazione su rivista::01a Articolo in rivista
Evaluation of the oncogenic risk of diffuse gastric polyposis. A case report / Spaziani, Erasmo; Marcello, Picchio; DI FILIPPO, Annalisa Romina; Narilli, Piero; Pacini, Luca; Moretti, Valentina; Pierino, Lucarelli; DE ANGELIS, Francesco; Ragona, Giuseppe; Petrozza, Vincenzo. - In: REVISTA ESPAÑOLA DE ENFERMEDADES DIGESTIVAS. - ISSN 1130-0108. - STAMPA. - 104:9(2012), pp. 493-496. [10.4321/s1130-01082012000900009]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/454093
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