Serum alkaline phosphatase activity, serum bone γ-carboxyglutamic acid protein, urinary hydroxyproline and bone mineral content were simultaneously measured in 30 age-matched pre- and postmenopausal women in order to define the temporal relationship between skeletal turnover and bone loss. In postmenopausal women, mean values of phosphatase activity, serum bone γ-carboxyglutamic acid protein and urinary hydroxyproline were significantly higher, and mean values of mineral content were significantly lower than in premenopausal women. A marked loss of bone mineral content together with a persistent increase in skeletal turnover is already evident shortly after the menopause.
CHANGES IN MINERAL-CONTENT AND BIOCHEMICAL BONE MARKERS AT THE MENOPAUSE / G., Mazzuoli; Minisola, Salvatore; C., Valtorta; R., Antonelli; S., Tabolli; F., Bigi. - In: ISRAEL JOURNAL OF MEDICAL SCIENCES. - ISSN 0021-2180. - ELETTRONICO. - 21:11(1985), pp. 875-877.
CHANGES IN MINERAL-CONTENT AND BIOCHEMICAL BONE MARKERS AT THE MENOPAUSE
MINISOLA, Salvatore;
1985
Abstract
Serum alkaline phosphatase activity, serum bone γ-carboxyglutamic acid protein, urinary hydroxyproline and bone mineral content were simultaneously measured in 30 age-matched pre- and postmenopausal women in order to define the temporal relationship between skeletal turnover and bone loss. In postmenopausal women, mean values of phosphatase activity, serum bone γ-carboxyglutamic acid protein and urinary hydroxyproline were significantly higher, and mean values of mineral content were significantly lower than in premenopausal women. A marked loss of bone mineral content together with a persistent increase in skeletal turnover is already evident shortly after the menopause.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
