The amounts of free sphingosine in Epstein Barr virus transformed B lymphocytes (EBV-B) treated with sphingosine and phorbol-12,13-dibutyrate (PD) has been quantified by high performance liquid chromatography (HPLC). PD treatment did not affect intracellular sphingosine level, while it seems to lessen the removal of this long chain base in sphingosine-treated EBV-B cells. The previous results relative to sphingosine-dependent changes in choline-metabolite levels have to be interpreted on the basis of these results.
Modulation of the free sphingosine levels in Epstein Barr virus transformed human B lymphocites by phorbol dibutyrate / Miccheli, Alfredo; R., Ricciolini; Lagana', Aldo; Piccolella, Enza; Conti, Filippo. - In: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. - ISSN 0167-4889. - STAMPA. - 1095:1(1991), pp. 90-92. [10.1016/0167-4889(91)90049-4]
Modulation of the free sphingosine levels in Epstein Barr virus transformed human B lymphocites by phorbol dibutyrate
MICCHELI, Alfredo;LAGANA', Aldo;PICCOLELLA, Enza;CONTI, Filippo
1991
Abstract
The amounts of free sphingosine in Epstein Barr virus transformed B lymphocytes (EBV-B) treated with sphingosine and phorbol-12,13-dibutyrate (PD) has been quantified by high performance liquid chromatography (HPLC). PD treatment did not affect intracellular sphingosine level, while it seems to lessen the removal of this long chain base in sphingosine-treated EBV-B cells. The previous results relative to sphingosine-dependent changes in choline-metabolite levels have to be interpreted on the basis of these results.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
