Dimethyl cathate was synthesized through a reaction sequence starting from 3,4-pyridinedicarboxylic acid anhydride, and hydrolyzed to the not yet described cathic acid. Pharmacological screening procedures only showed a protection against the convulsive effect of pentylenetetrazol.

Dimethyl cathate: synthesis and pharmacological investigation / Stein, Maria Luisa; Nencini, Paolo. - In: IL FARMACO. - ISSN 0014-827X. - 44:(1989), pp. 959-965.

Dimethyl cathate: synthesis and pharmacological investigation.

STEIN, Maria Luisa;NENCINI, Paolo
1989

Abstract

Dimethyl cathate was synthesized through a reaction sequence starting from 3,4-pyridinedicarboxylic acid anhydride, and hydrolyzed to the not yet described cathic acid. Pharmacological screening procedures only showed a protection against the convulsive effect of pentylenetetrazol.
1989
Analgesics; chemical synthesis, Animals, Anticonvulsants; chemical synthesis, Chemical Phenomena, Chemistry, Dose-Response Relationship; Drug, Lethal Dose 50, Male, Mice, Nicotinic Acids; chemical synthesis/pharmacology/toxicity, Pentylenetetrazole, Seizures; chemically induced/prevention /&/ control
01 Pubblicazione su rivista::01a Articolo in rivista
Dimethyl cathate: synthesis and pharmacological investigation / Stein, Maria Luisa; Nencini, Paolo. - In: IL FARMACO. - ISSN 0014-827X. - 44:(1989), pp. 959-965.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/452712
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