Behavioral and biochemical analysis of the effects of stress on brain dopamine (DA) functioning in two inbred strains of mice reveals opposite patterns of adaptation to chronic stress. Chronically stressed mice of the C57BL/6 (C57) strain are characterized by hypersensitive mesolimbic DA autoreceptors and by a dramatic increase of D1/D2 DA receptor ratio (possibly postsynaptic) in the nucleus accumbens septi (NAS) as revealed by in vivo binding of 3 H-spiperone and 3 H-SCH23390. Chronically stressed DBA/2 (DBA) ...
Role of genotype in the adaptation of the brain dopamine system to stress / PUGLISI ALLEGRA, Stefano; E., Kempf; Cabib, Simona. - In: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. - ISSN 0149-7634. - STAMPA. - 14:(1991), pp. 523-528.
Role of genotype in the adaptation of the brain dopamine system to stress
PUGLISI ALLEGRA, Stefano;CABIB, Simona
1991
Abstract
Behavioral and biochemical analysis of the effects of stress on brain dopamine (DA) functioning in two inbred strains of mice reveals opposite patterns of adaptation to chronic stress. Chronically stressed mice of the C57BL/6 (C57) strain are characterized by hypersensitive mesolimbic DA autoreceptors and by a dramatic increase of D1/D2 DA receptor ratio (possibly postsynaptic) in the nucleus accumbens septi (NAS) as revealed by in vivo binding of 3 H-spiperone and 3 H-SCH23390. Chronically stressed DBA/2 (DBA) ...I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
