Electroconvulsive shock (ECS)-induced seizures present a clear cut diurnal rhythmicity when BALB/c mice are subjected to a light-dark (L/D) schedule. On the contrary, in the absence of external synchronizers no evident fluctuations in epileptic behaviour were evident. Naloxone decreased the threshold of ECS-induced convulsions, thus confirming an involvement of opioids in this type of behaviour. These findings indicate that opioids present a diurnal (L/D) but not circadian (L/L) rhythmicity in BALB/c mice.

Diurnal variations in electroconvulsive shock-induced seizures: involvement of endogenous opioids / Oliverio, Alberto; C., Castellano; PUGLISI ALLEGRA, Stefano; Renzi, Paolo. - In: NEUROSCIENCE LETTERS. - ISSN 0304-3940. - STAMPA. - 57(1985), pp. 237-240. [10.1016/0304-3940(85)90497-5]

Diurnal variations in electroconvulsive shock-induced seizures: involvement of endogenous opioids.

OLIVERIO, Alberto;PUGLISI ALLEGRA, Stefano;RENZI, Paolo
1985

Abstract

Electroconvulsive shock (ECS)-induced seizures present a clear cut diurnal rhythmicity when BALB/c mice are subjected to a light-dark (L/D) schedule. On the contrary, in the absence of external synchronizers no evident fluctuations in epileptic behaviour were evident. Naloxone decreased the threshold of ECS-induced convulsions, thus confirming an involvement of opioids in this type of behaviour. These findings indicate that opioids present a diurnal (L/D) but not circadian (L/L) rhythmicity in BALB/c mice.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/452109
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