A dark phase increase in pain sensitivity was evident in C57BL/6 inbred mice. On the contrary Swiss mice are characterized by decreased nocturnal pain sensitivity. The latter finding is in agreement with a number of previous studies based on albino mice. However, our findings indicate that (1) nocturnal decreased pain sensitivity is not the rule in the mouse and (2) large differences are evident when the onset in peak nocturnal analgesia is considered.
Genetic differences in daily rhythms of pain sensitivity in mice / C., Castellano; PUGLISI ALLEGRA, Stefano; Renzi, Paolo; Oliverio, Alberto. - In: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. - ISSN 0091-3057. - STAMPA. - 23:(1985), pp. 91-92. [10.1016/0091-3057(85)90135-2]
Genetic differences in daily rhythms of pain sensitivity in mice.
PUGLISI ALLEGRA, Stefano;RENZI, Paolo;OLIVERIO, Alberto
1985
Abstract
A dark phase increase in pain sensitivity was evident in C57BL/6 inbred mice. On the contrary Swiss mice are characterized by decreased nocturnal pain sensitivity. The latter finding is in agreement with a number of previous studies based on albino mice. However, our findings indicate that (1) nocturnal decreased pain sensitivity is not the rule in the mouse and (2) large differences are evident when the onset in peak nocturnal analgesia is considered.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
