Abstract Serum bile acids were determined in 13 cirrhotic patients with portacaval shunt and in 15 with mesocaval shunt. 20 nonshunted cirrhotics were used as controls. Serum bile acid levels were higher in portacaval (26.7 +/- 14.3 micrograms/ml) than in mesocaval shunt patients (16.9 +/- 8.1 micrograms/ml) and controls (14.1 +/- 11.5 micrograms/ml). The cholic/chenodeoxycholic ratio was lower after portacaval shunt than after mesocaval shunt (0.36 +/- 0.15 and 0.63 +/- 0.26, respectively). It is hypothesized that these findings may be consistent with a larger hepatic blood flow present in mesocaval shunted patients and with chenodeoxycholic absorption in the upper small intestine.

Differences in serum bile acid composition between unoperated cirrhotic patients and patients with portacaval or mesocaval shunt / Angelico, Mario; Attili, Adolfo Francesco; A., Cantafora; M., Lombardi; A., Thau; Capocaccia, Livio. - In: DIGESTION. - ISSN 0012-2823. - STAMPA. - 19:2(1979), pp. 126-130.

Differences in serum bile acid composition between unoperated cirrhotic patients and patients with portacaval or mesocaval shunt

ANGELICO, Mario;ATTILI, Adolfo Francesco;CAPOCACCIA, Livio
1979

Abstract

Abstract Serum bile acids were determined in 13 cirrhotic patients with portacaval shunt and in 15 with mesocaval shunt. 20 nonshunted cirrhotics were used as controls. Serum bile acid levels were higher in portacaval (26.7 +/- 14.3 micrograms/ml) than in mesocaval shunt patients (16.9 +/- 8.1 micrograms/ml) and controls (14.1 +/- 11.5 micrograms/ml). The cholic/chenodeoxycholic ratio was lower after portacaval shunt than after mesocaval shunt (0.36 +/- 0.15 and 0.63 +/- 0.26, respectively). It is hypothesized that these findings may be consistent with a larger hepatic blood flow present in mesocaval shunted patients and with chenodeoxycholic absorption in the upper small intestine.
1979
01 Pubblicazione su rivista::01a Articolo in rivista
Differences in serum bile acid composition between unoperated cirrhotic patients and patients with portacaval or mesocaval shunt / Angelico, Mario; Attili, Adolfo Francesco; A., Cantafora; M., Lombardi; A., Thau; Capocaccia, Livio. - In: DIGESTION. - ISSN 0012-2823. - STAMPA. - 19:2(1979), pp. 126-130.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/451655
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