The repeated sequence TTAGGG is present at all tested vertebrate telomeres including those of humans and at the telomeres of evolutionarily very distant organisms such as trypanosomes and slime moulds. We tested for the presence of this sequence in the genome of the crustacean isopod Asetlus aquaticus. Fluorescence in situ hybridization and BAL3 1 nuclease digestion demonstrate that the (TTAGGG),, sequence occurs at the extreme termini of the chromosomes and also at an interstitial site.
The telomeric sequences of Asellus aquaticus (Crust. Isop.) / Pelliccia, Franca; Volpi, E. V.; Lanza, V.; Gaddini, L. BALDINI A.; Rocchi, Angela. - In: HEREDITY. - ISSN 0018-067X. - STAMPA. - 72:(1994), pp. 78-80. [10.1038/hdy.1994.9]
The telomeric sequences of Asellus aquaticus (Crust. Isop.).
PELLICCIA, Franca;ROCCHI, Angela
1994
Abstract
The repeated sequence TTAGGG is present at all tested vertebrate telomeres including those of humans and at the telomeres of evolutionarily very distant organisms such as trypanosomes and slime moulds. We tested for the presence of this sequence in the genome of the crustacean isopod Asetlus aquaticus. Fluorescence in situ hybridization and BAL3 1 nuclease digestion demonstrate that the (TTAGGG),, sequence occurs at the extreme termini of the chromosomes and also at an interstitial site.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
