We have studied the T-cell processing pathways of Hepatitis B antigens and the role of specific B lymphocytes. It could be shown that some form of processing by specific B cells is required for class I CTLs. This mechanism differs from class II endosomal processing. In addition, it could be shown that lysis of HBsAg-specific B cells may be partly responsible for chronic HBV carrier states.
T-CELL RECOGNITION OF HEPATITIS-B ENVELOPE PROTEINS / Barnaba, Vincenzo; A., Franco; Paroli, Marino; R., Benvenuto; I., Santilio; F., Balsano. - In: ARCHIVES OF VIROLOGY. - ISSN 0304-8608. - 4:4(1992), pp. 19-22.
T-CELL RECOGNITION OF HEPATITIS-B ENVELOPE PROTEINS
BARNABA, Vincenzo;PAROLI, Marino;
1992
Abstract
We have studied the T-cell processing pathways of Hepatitis B antigens and the role of specific B lymphocytes. It could be shown that some form of processing by specific B cells is required for class I CTLs. This mechanism differs from class II endosomal processing. In addition, it could be shown that lysis of HBsAg-specific B cells may be partly responsible for chronic HBV carrier states.File allegati a questo prodotto
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