A microdosimetric analysis using ideal and real pulses was carried out in this paper. To perform this goal, authors employed an algorithm developed recently for nsPEF based on Laplace's equation and able to take into account cell compartment dispersivity. A comparison between biphasic real and ideal waveforms was carried out. The ideal pulse induced the highest pore density efficiency, hence evidencing that a device optimization to avoid waveform degradation and losses has a fundamental impact on the performances of the delivered pulses at the single cell level. © 2011 IEEE.
Microdosimetry applied to nanosecond pulsed electric fields: A comparison on a single cell between real and ideal waveforms / Caterina, Merla; Paffi, Alessandra; Apollonio, Francesca; Philippe, Leveque; Liberti, Micaela. - ELETTRONICO. - (2011), pp. 302-305. (Intervento presentato al convegno 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 tenutosi a Boston, MA nel 30 August 2011 through 3 September 2011) [10.1109/iembs.2011.6090079].
Microdosimetry applied to nanosecond pulsed electric fields: A comparison on a single cell between real and ideal waveforms
PAFFI, ALESSANDRA;APOLLONIO, Francesca;LIBERTI, Micaela
2011
Abstract
A microdosimetric analysis using ideal and real pulses was carried out in this paper. To perform this goal, authors employed an algorithm developed recently for nsPEF based on Laplace's equation and able to take into account cell compartment dispersivity. A comparison between biphasic real and ideal waveforms was carried out. The ideal pulse induced the highest pore density efficiency, hence evidencing that a device optimization to avoid waveform degradation and losses has a fundamental impact on the performances of the delivered pulses at the single cell level. © 2011 IEEE.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
