Several genes encoding salivary components of the mosquito Anopheles gambiae were identified using a selective trapping approach. Among these, five corresponded to genes expressed specifically in female glands and their role may possibly be linked to blood-feeding. Our collection included a fourth member of the D7 protein family and two polypep tides that showed weak similarity to anti-coagulants from distantly related species. Moreover, we identified two additional members of a novel group of proteins that we named glandins. The isolation of tissue-specific genes represents a first step toward a deeper molecular analysis of mosquito salivary, secretions. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
Novel cDNAs encoding salivary proteins from the malaria vector Anopheles gambiae / Lanfrancotti, Alessandra; Lombardo, Fabrizio; Santolamazza, Federica; Massimiliano, Veneri; Tiziana, Castrignano; COLUZZI BARTOCCIONI, Caio Mario; Arca', Bruno. - In: FEBS LETTERS. - ISSN 0014-5793. - STAMPA. - 517:1-3(2002), pp. 67-71. [10.1016/s0014-5793(02)02578-4]
Novel cDNAs encoding salivary proteins from the malaria vector Anopheles gambiae
LANFRANCOTTI, Alessandra;LOMBARDO, Fabrizio;SANTOLAMAZZA, FEDERICA;COLUZZI BARTOCCIONI, Caio Mario;ARCA', Bruno
2002
Abstract
Several genes encoding salivary components of the mosquito Anopheles gambiae were identified using a selective trapping approach. Among these, five corresponded to genes expressed specifically in female glands and their role may possibly be linked to blood-feeding. Our collection included a fourth member of the D7 protein family and two polypep tides that showed weak similarity to anti-coagulants from distantly related species. Moreover, we identified two additional members of a novel group of proteins that we named glandins. The isolation of tissue-specific genes represents a first step toward a deeper molecular analysis of mosquito salivary, secretions. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
