We report on a 4-year-old boy with recurrent giant-cell fibroblastoma of the right nasal genal region, Histologic examination revealed that both lesions were constituted of spindle and stellate cells and a minor amount of multinucleated giant cells in a myxoid stroma containing cisternal-like spaces. Immunohistochemical examination revealed positivity for vimentin in both cellular components. Ultra-structural examination showed, in some spindle and multinucleated cells, two kinds of intracellular crystalline inclusions, located, respectively, in the cisternae of the rough endoplasmic reticulum and, apparently free, in the cytoplasm. To the best of our knowledge, this case, unusual for its location, is the first example of giant-cell fibroblastoma bearing intracellular crystalline inclusions.

UNUSUAL ULTRASTRUCTURAL FINDINGS IN GIANT-CELL FIBROBLASTOMA / C., Bosman; R., Boldrini; V., Pierro; Corsi, Alessandro. - In: TUMORI. - ISSN 0300-8916. - 81:4(1995), pp. 283-289.

UNUSUAL ULTRASTRUCTURAL FINDINGS IN GIANT-CELL FIBROBLASTOMA

CORSI, ALESSANDRO
1995

Abstract

We report on a 4-year-old boy with recurrent giant-cell fibroblastoma of the right nasal genal region, Histologic examination revealed that both lesions were constituted of spindle and stellate cells and a minor amount of multinucleated giant cells in a myxoid stroma containing cisternal-like spaces. Immunohistochemical examination revealed positivity for vimentin in both cellular components. Ultra-structural examination showed, in some spindle and multinucleated cells, two kinds of intracellular crystalline inclusions, located, respectively, in the cisternae of the rough endoplasmic reticulum and, apparently free, in the cytoplasm. To the best of our knowledge, this case, unusual for its location, is the first example of giant-cell fibroblastoma bearing intracellular crystalline inclusions.
1995
giant-cell fibroblastoma; intracellular crystalline inclusions; soft tissue tumor; ultrastructure
01 Pubblicazione su rivista::01a Articolo in rivista
UNUSUAL ULTRASTRUCTURAL FINDINGS IN GIANT-CELL FIBROBLASTOMA / C., Bosman; R., Boldrini; V., Pierro; Corsi, Alessandro. - In: TUMORI. - ISSN 0300-8916. - 81:4(1995), pp. 283-289.
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/438173
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 2
social impact