In many species, both morphological and molecular traits related to sex and reproduction evolve faster in males than in females. Ultimately, rapid male evolution relies on the acquisition of genetic variation associated with differential reproductive success. Many newly evolved genes are associated with novel functions that might enhance male fitness. However, functional evidence of the adaptive role of recently originated genes in males is still lacking. The Sperm dynein intermediate chain multigene family, which encodes a Sperm dynein intermediate chain presumably involved in sperm motility, originated from complex genetic rearrangements in the lineage that leads to Drosophila melanogaster within the last 5.4 million years since its split from Drosophila simulans. We deleted all the members of this multigene family resident on the X chromosome of D. melanogaster by chromosome engineering and found that, although the deletion does not result in a reduction of progeny number, it impairs the competence of the sperm in the presence of sperm from wild-type males. Therefore, the Sperm dynein intermediate chain multigene family contributes to the differential reproductive success among males and illustrates precisely how quickly a new gene function can be incorporated into the genetic network of a species.

Functional evidence that a newly evolved Drosophila sperm-specific gene boost sperm competition / S. D., Yeh; T., Do; C., Chan; A., Cordova; F., Carranza; E. A., Yamamoto; M., Abbassi; K. A., Gandasetiawan; P., Librado; E., Damia; Dimitri, Patrizio; J., Rozas; D. L., Hartl; J., Roote; J. M., Ranz. - In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. - ISSN 0027-8424. - STAMPA. - 106:(2012), pp. 2043-2048. [10.1073/pnas.1121327109]

Functional evidence that a newly evolved Drosophila sperm-specific gene boost sperm competition.

DIMITRI, Patrizio;
2012

Abstract

In many species, both morphological and molecular traits related to sex and reproduction evolve faster in males than in females. Ultimately, rapid male evolution relies on the acquisition of genetic variation associated with differential reproductive success. Many newly evolved genes are associated with novel functions that might enhance male fitness. However, functional evidence of the adaptive role of recently originated genes in males is still lacking. The Sperm dynein intermediate chain multigene family, which encodes a Sperm dynein intermediate chain presumably involved in sperm motility, originated from complex genetic rearrangements in the lineage that leads to Drosophila melanogaster within the last 5.4 million years since its split from Drosophila simulans. We deleted all the members of this multigene family resident on the X chromosome of D. melanogaster by chromosome engineering and found that, although the deletion does not result in a reduction of progeny number, it impairs the competence of the sperm in the presence of sperm from wild-type males. Therefore, the Sperm dynein intermediate chain multigene family contributes to the differential reproductive success among males and illustrates precisely how quickly a new gene function can be incorporated into the genetic network of a species.
2012
01 Pubblicazione su rivista::01a Articolo in rivista
Functional evidence that a newly evolved Drosophila sperm-specific gene boost sperm competition / S. D., Yeh; T., Do; C., Chan; A., Cordova; F., Carranza; E. A., Yamamoto; M., Abbassi; K. A., Gandasetiawan; P., Librado; E., Damia; Dimitri, Patrizio; J., Rozas; D. L., Hartl; J., Roote; J. M., Ranz. - In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. - ISSN 0027-8424. - STAMPA. - 106:(2012), pp. 2043-2048. [10.1073/pnas.1121327109]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/435242
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