The interaction between Na-DNA and divalent metal cations (Mg2+, Mn2+, Co2+ and Ni2+) has been investigated by 23Na NMR relaxation. The experimental data have been interpreted in terms of Manning's counterion condensation theory and a two-site exchange for the sodium ions. The experiments showed that Mn2+ affects the polyion surface atmosphere in a different way from the other metal ions. This behaviour may be due to sugar puckering transition of the DNA induced by Mn2+.

Interaction of divalent metal ions with DNA investigated by 23Na NMR relaxation / F. C., Marincola; Mariano, Casu; Giuseppe, Saba; Manetti, Cesare; Adolfo, Lai. - In: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. - ISSN 1463-9076. - STAMPA. - 2:10(2000), pp. 2425-2428. [10.1039/b000433m]

Interaction of divalent metal ions with DNA investigated by 23Na NMR relaxation

MANETTI, Cesare;
2000

Abstract

The interaction between Na-DNA and divalent metal cations (Mg2+, Mn2+, Co2+ and Ni2+) has been investigated by 23Na NMR relaxation. The experimental data have been interpreted in terms of Manning's counterion condensation theory and a two-site exchange for the sodium ions. The experiments showed that Mn2+ affects the polyion surface atmosphere in a different way from the other metal ions. This behaviour may be due to sugar puckering transition of the DNA induced by Mn2+.
2000
01 Pubblicazione su rivista::01a Articolo in rivista
Interaction of divalent metal ions with DNA investigated by 23Na NMR relaxation / F. C., Marincola; Mariano, Casu; Giuseppe, Saba; Manetti, Cesare; Adolfo, Lai. - In: PHYSICAL CHEMISTRY CHEMICAL PHYSICS. - ISSN 1463-9076. - STAMPA. - 2:10(2000), pp. 2425-2428. [10.1039/b000433m]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/43359
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