Treatment of (hetero)aryl halides with 2-(1-alkynyl)benzoic acids or (Z)-2-en-4-ynoic acids in the pre- sence of K2CO3 and a catalytic amount of Pd(PPh3)4 provides reaction mixtures in which stereode®ned 3-[(1,1-unsymetrically disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereode®ned 5-[(1,1-unsym- metrically disubstituted)methylidene]furan-2(5H)-ones, respectively, are the major products. # 2000 Elsevier Science Ltd. All rights reserved.
Palladium-catalyzed synthesis of sterodefined 3-[(1,1-unsymmetrically dusubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[(1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones / R., Rossi; F., Bellina; A., Biagetti; A., Catanese; Mannina, Luisa. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - ELETTRONICO. - 41:(2000), pp. 5281-5286. [10.1016/S0040-4039(00)00806-6]
Palladium-catalyzed synthesis of sterodefined 3-[(1,1-unsymmetrically dusubstituted)methylidene]isobenzofuran-1(3H)-ones and stereodefined 5-[(1,1-unsymmetrically disubstituted)methylidene]furan-2(5H)-ones
MANNINA, LUISA
2000
Abstract
Treatment of (hetero)aryl halides with 2-(1-alkynyl)benzoic acids or (Z)-2-en-4-ynoic acids in the pre- sence of K2CO3 and a catalytic amount of Pd(PPh3)4 provides reaction mixtures in which stereode®ned 3-[(1,1-unsymetrically disubstituted)methylidene]isobenzofuran-1(3H)-ones and stereode®ned 5-[(1,1-unsym- metrically disubstituted)methylidene]furan-2(5H)-ones, respectively, are the major products. # 2000 Elsevier Science Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
