Monoclonal antibodies, which include murine, chimeric, humanised and fully human antibodies, bind to their target receptors with high affinity and specificity. In the last two decades several different monoclonal antibodies have been approved by the Food and Drug Administration for therapeutic purposes, and some of these and others have also been radiolabelled for diagnostic and therapeutic purposes. This field is in continuous evolution and this overview highlights the role of radiolabelled antibodies in research and clinical setting.

An overview of the diagnostic and therapeutic use of monoclonal antibodies in medicine / S. J., Goldsmith; Signore, Alberto. - In: THE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. - ISSN 1824-4785. - STAMPA. - 54:6(2010), pp. 574-581.

An overview of the diagnostic and therapeutic use of monoclonal antibodies in medicine

SIGNORE, Alberto
2010

Abstract

Monoclonal antibodies, which include murine, chimeric, humanised and fully human antibodies, bind to their target receptors with high affinity and specificity. In the last two decades several different monoclonal antibodies have been approved by the Food and Drug Administration for therapeutic purposes, and some of these and others have also been radiolabelled for diagnostic and therapeutic purposes. This field is in continuous evolution and this overview highlights the role of radiolabelled antibodies in research and clinical setting.
2010
antibodies; monoclonal; decision support techniques; diagnostic use/therapeutic use; humans; infection; inflammation; isotope labeling; molecular imaging; radioimmunodetection; radioisotopes; radionuclide imaging/therapy; radiopharmaceuticals; trends
01 Pubblicazione su rivista::01a Articolo in rivista
An overview of the diagnostic and therapeutic use of monoclonal antibodies in medicine / S. J., Goldsmith; Signore, Alberto. - In: THE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. - ISSN 1824-4785. - STAMPA. - 54:6(2010), pp. 574-581.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/423695
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