A furanosic derivative has been identified as a simple sialylmimetic and synthesized, representing the first step in the development of a new series of furanosic sialic acid's mimetics as potential inhibitors of influenza virus neuraminidase. The structure was tested on a molecular simulating environment before proceeding with synthetic pathways.
Design and synthesis of a new furanosic sialylmimetic as a potential influenza neuraminidase viral inhibitor / Bianco, Armandodoriano; Brufani, Mario; Dri, D. A.; Melchioni, C.; Filocamo, Luigi. - In: LETTERS IN ORGANIC CHEMISTRY. - ISSN 1570-1786. - STAMPA. - 2:1(2005), pp. 83-88. [10.2174/1570178053400207]
Design and synthesis of a new furanosic sialylmimetic as a potential influenza neuraminidase viral inhibitor
BIANCO, Armandodoriano;BRUFANI, Mario;D. A. Dri;FILOCAMO, Luigi
2005
Abstract
A furanosic derivative has been identified as a simple sialylmimetic and synthesized, representing the first step in the development of a new series of furanosic sialic acid's mimetics as potential inhibitors of influenza virus neuraminidase. The structure was tested on a molecular simulating environment before proceeding with synthetic pathways.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
