Eight ALL patients displaying a CD7 +, TdT +, CD10 -, T MoAbs -, myeloid MoAbs -, AP + phenotype are described. Some patients showed well-known risk factors such as cytogenetic abnormalities, high WBC count, mediastinal mass, and/or organomegalies. The clinical behaviour was very poor and only one patient is in CR and off therapy. Therefore such a pre-T phenotype, although sometimes associated with the other risk factors, could be considered a poor prognosis phenotype.
CALLA-negative, TdT- and CD7-positive acute lymphoblastic leukemia: A phenotype associated with poor prognosis / G., De Rossi; Cafolla, Arturo; R., Gastaldi; F., Lo Coco; M., Lopez; M., Luciani; Pasqualetti, Daniela; A. M., Testi; Mandelli, Franco; ALOE SPIRITI, Maria Antonietta. - In: DIAGNOSTIC AND CLINICAL IMMUNOLOGY. - ISSN 0895-0458. - 5:3(1987), pp. 140-143.
CALLA-negative, TdT- and CD7-positive acute lymphoblastic leukemia: A phenotype associated with poor prognosis
CAFOLLA, Arturo;PASQUALETTI, Daniela;MANDELLI, Franco;ALOE SPIRITI, Maria Antonietta
1987
Abstract
Eight ALL patients displaying a CD7 +, TdT +, CD10 -, T MoAbs -, myeloid MoAbs -, AP + phenotype are described. Some patients showed well-known risk factors such as cytogenetic abnormalities, high WBC count, mediastinal mass, and/or organomegalies. The clinical behaviour was very poor and only one patient is in CR and off therapy. Therefore such a pre-T phenotype, although sometimes associated with the other risk factors, could be considered a poor prognosis phenotype.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
