Eight ALL patients displaying a CD7 +, TdT +, CD10 -, T MoAbs -, myeloid MoAbs -, AP + phenotype are described. Some patients showed well-known risk factors such as cytogenetic abnormalities, high WBC count, mediastinal mass, and/or organomegalies. The clinical behaviour was very poor and only one patient is in CR and off therapy. Therefore such a pre-T phenotype, although sometimes associated with the other risk factors, could be considered a poor prognosis phenotype.
CALLA-negative, TdT- and CD7-positive acute lymphoblastic leukemia: A phenotype associated with poor prognosis / G., De Rossi; M. A., Aloe Spiriti; Cafolla, Arturo; R., Gastaldi; F., Lo Coco; M., Lopez; M., Luciani; Pasqualetti, Daniela; A. M., Testi; Mandelli, Franco. - In: DIAGNOSTIC AND CLINICAL IMMUNOLOGY. - ISSN 0895-0458. - 5:3(1987), pp. 140-143.
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Titolo: | CALLA-negative, TdT- and CD7-positive acute lymphoblastic leukemia: A phenotype associated with poor prognosis | |
Autori: | ||
Data di pubblicazione: | 1987 | |
Rivista: | ||
Citazione: | CALLA-negative, TdT- and CD7-positive acute lymphoblastic leukemia: A phenotype associated with poor prognosis / G., De Rossi; M. A., Aloe Spiriti; Cafolla, Arturo; R., Gastaldi; F., Lo Coco; M., Lopez; M., Luciani; Pasqualetti, Daniela; A. M., Testi; Mandelli, Franco. - In: DIAGNOSTIC AND CLINICAL IMMUNOLOGY. - ISSN 0895-0458. - 5:3(1987), pp. 140-143. | |
Handle: | http://hdl.handle.net/11573/419570 | |
Appartiene alla tipologia: | 01a Articolo in rivista |