The present study deals with the appropriate statistical approach to the histomorphometric technique carried out on bone tissue with the Merz and Schenk integrating eyepiece. Statistical analysis of the results obtained from ten bone biopsies of renal osteodystrophic patients enabled to calculate the values of standard errors for each histomorphometric parameter as a function of measured histological fields. The examination of 42 fields chosen at random on histological sections from different sites of the bone biopsy guarantees sufficiently low standard error values. This technique is of invaluable help in the study of metabolic bone diseases, and extremely useful in the evaluation of treatment trials in renal osteodystrophy.

[Bone histomorphometry: methodological criteria in the study of metabolic skeletal diseases] / Coen, Giorgio; Ballanti, Paola; M., Taccone Gallucci; A. R., Bianchi; Bianchini, Gabriella; Mazzaferro, Sandro; I., Milletti; G. A., Cinotti. - In: BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE. - ISSN 0037-8771. - 57:18(1981).

[Bone histomorphometry: methodological criteria in the study of metabolic skeletal diseases].

COEN, Giorgio;BALLANTI, Paola;BIANCHINI, Gabriella;MAZZAFERRO, SANDRO;
1981

Abstract

The present study deals with the appropriate statistical approach to the histomorphometric technique carried out on bone tissue with the Merz and Schenk integrating eyepiece. Statistical analysis of the results obtained from ten bone biopsies of renal osteodystrophic patients enabled to calculate the values of standard errors for each histomorphometric parameter as a function of measured histological fields. The examination of 42 fields chosen at random on histological sections from different sites of the bone biopsy guarantees sufficiently low standard error values. This technique is of invaluable help in the study of metabolic bone diseases, and extremely useful in the evaluation of treatment trials in renal osteodystrophy.
1981
01 Pubblicazione su rivista::01a Articolo in rivista
[Bone histomorphometry: methodological criteria in the study of metabolic skeletal diseases] / Coen, Giorgio; Ballanti, Paola; M., Taccone Gallucci; A. R., Bianchi; Bianchini, Gabriella; Mazzaferro, Sandro; I., Milletti; G. A., Cinotti. - In: BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE. - ISSN 0037-8771. - 57:18(1981).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/418468
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