After interruption of highly active antiretroviral therapy, 15 out of 53 patients with the X4 HIV strain had a significantly larger decrease in CD4(+) T cell count (P = 0.001) and shorter length of treatment interruption (P = 0.02) than patients with the R5 strain. At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain.

Switching of Inferred Tropism Caused by HIV during Interruption of Antiretroviral Therapy / L., Sarmati; S. G., Parisi; Andreoni, Carolina; E., Nicastri; A. R., Buonomini; C., Boldrin; L., Dori; M., Montano; C., Tommasi; S., Andreis; Vullo, Vincenzo; G., Palu; M., Andreoni. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - 48:7(2010), pp. 2586-2588. [10.1128/jcm.02125-09]

Switching of Inferred Tropism Caused by HIV during Interruption of Antiretroviral Therapy

ANDREONI, CAROLINA;VULLO, Vincenzo;
2010

Abstract

After interruption of highly active antiretroviral therapy, 15 out of 53 patients with the X4 HIV strain had a significantly larger decrease in CD4(+) T cell count (P = 0.001) and shorter length of treatment interruption (P = 0.02) than patients with the R5 strain. At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain.
2010
01 Pubblicazione su rivista::01a Articolo in rivista
Switching of Inferred Tropism Caused by HIV during Interruption of Antiretroviral Therapy / L., Sarmati; S. G., Parisi; Andreoni, Carolina; E., Nicastri; A. R., Buonomini; C., Boldrin; L., Dori; M., Montano; C., Tommasi; S., Andreis; Vullo, Vincenzo; G., Palu; M., Andreoni. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - 48:7(2010), pp. 2586-2588. [10.1128/jcm.02125-09]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/417695
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