2-cephem allylic bromides are important, versatile intermediates for the derivatization of C-3’ position in cephalosporines. We showed that they can react smoothly with phenols, yielding the C-3’ cephem derivatives by C-alkylation of phenols.
Reaction of 3-halomethyl-2-cephem derivatives with phenols / Grgurina, Ingeborg; Nicoletti, Rosario. - STAMPA. - 3(2):(1981), pp. 599-602. (Intervento presentato al convegno I International Conference on Chemistry and Biotechnology of Biologically Active Natural Products tenutosi a Varna ( Bulgaria) nel 21-26 Sept).
Reaction of 3-halomethyl-2-cephem derivatives with phenols
GRGURINA, Ingeborg;NICOLETTI, Rosario
1981
Abstract
2-cephem allylic bromides are important, versatile intermediates for the derivatization of C-3’ position in cephalosporines. We showed that they can react smoothly with phenols, yielding the C-3’ cephem derivatives by C-alkylation of phenols.File allegati a questo prodotto
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