Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with "low-risk" or stage I "intermediate-risk" WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy. © 2006 Elsevier Inc. All rights reserved.
Nephron-sparing surgery in children with primary renal tumor: Indications and results / Cozzi, Denis; Zani, Augusto. - In: SEMINARS IN PEDIATRIC SURGERY. - ISSN 1055-8586. - 15:1(2006), pp. 3-9. [10.1053/j.sempedsurg.2005.11.002]
Nephron-sparing surgery in children with primary renal tumor: Indications and results
COZZI, Denis;ZANI, AUGUSTO
2006
Abstract
Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with "low-risk" or stage I "intermediate-risk" WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy. © 2006 Elsevier Inc. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
