How is spatial information for limb movement encoded in the brain? Computational and psychophysical studies suggest that beginning hand position, via-points, and target are specified relative to the body to afford a comparison between the sensory (e.g., kinesthetic) reafferences and the commands that generate limb movement. Here we propose that the superior parietal lobule (Brodmann area 5) might represent a substrate for a body-centered positional code. Monkeys made arm movements in different parts of 3D space in a reaction-time task. We found that the activity of area 5 neurons can be related to either the starting point, dr the final point, or combinations of the two. Neural activity is monotonically tuned in a body-centered frame of reference, whose coordinates define the azimuth, elevation, and distance of the hand. Each spatial coordinate tends to be encoded in a different sub population of neurons. This parcellation could be a neural correlate of the psychophysical observation that these spatial parameters are processed in parallel and largely independent of each other in man.

REPRESENTING SPATIAL INFORMATION FOR LIMB MOVEMENT - ROLE OF AREA 5 IN THE MONKEY / Lacquaniti, F; Guigon, E; Bianchi, L; Ferraina, Stefano; Caminiti, Roberto. - In: CEREBRAL CORTEX. - ISSN 1047-3211. - 5:(1995), pp. 391-409. [10.1093/cercor/5.5.391]

REPRESENTING SPATIAL INFORMATION FOR LIMB MOVEMENT - ROLE OF AREA 5 IN THE MONKEY

FERRAINA, Stefano;CAMINITI, Roberto
1995

Abstract

How is spatial information for limb movement encoded in the brain? Computational and psychophysical studies suggest that beginning hand position, via-points, and target are specified relative to the body to afford a comparison between the sensory (e.g., kinesthetic) reafferences and the commands that generate limb movement. Here we propose that the superior parietal lobule (Brodmann area 5) might represent a substrate for a body-centered positional code. Monkeys made arm movements in different parts of 3D space in a reaction-time task. We found that the activity of area 5 neurons can be related to either the starting point, dr the final point, or combinations of the two. Neural activity is monotonically tuned in a body-centered frame of reference, whose coordinates define the azimuth, elevation, and distance of the hand. Each spatial coordinate tends to be encoded in a different sub population of neurons. This parcellation could be a neural correlate of the psychophysical observation that these spatial parameters are processed in parallel and largely independent of each other in man.
1995
01 Pubblicazione su rivista::01a Articolo in rivista
REPRESENTING SPATIAL INFORMATION FOR LIMB MOVEMENT - ROLE OF AREA 5 IN THE MONKEY / Lacquaniti, F; Guigon, E; Bianchi, L; Ferraina, Stefano; Caminiti, Roberto. - In: CEREBRAL CORTEX. - ISSN 1047-3211. - 5:(1995), pp. 391-409. [10.1093/cercor/5.5.391]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/41449
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