Preliminary results on toxicology and mutagenic effects of buckypaper (BP) of multiwalled carbon nanotubes (MWCNTs) on metabolism and immunological modification in vivo and in vitro
The aim of our research is focused on the biological effects of BP and functionalized MWCNTs in laboratory animals in vivo, on the immunological buckypaper effects on mice and the effects of functionalized MWCNTs on five different cell types (CaCo-2 Colorectal Carcinoma cell line; MCF-7 human breast carcinoma cell line, HL-60 human promyelocytic leukaemia cell line; HASMC normal human artery smooth muscle cells and finally HF normal human fibroblasts). Finally, the potential mutagenicity of MWCNTs was studied in bacterial reverse mutation assay. Nanomaterials possible applications in surgery, cancer therapy and new imaging techniques involve large numbers of researchers and potential patients. It is important to assess the potential health risks related to their exposure to nanoparticles.
Preliminary results on toxicology and mutagenic effects of buckypaper (BP) of multiwalled carbon nanotubes (MWCNTs) on metabolism and immunological modification in vivo and in vitro / Chiaretti, Massimo; Cucina, Alessandra; Bellucci, S.; DI SOTTO, Antonella; Mazzanti, Gabriela; Bosco, Sandro; Le Foche, F.; Carru, Giovanna Angela; Masciangelo, Raffaele; Chiaretti, A. M.; DE BELLIS, Giovanni; Micciulla, F.; Chiaretti, A. I.; Faiola, Fabio; Nicoletti, Carmine; D’Amore, E.; Pacioni, F.; Antonini, R.. - ELETTRONICO. - (2009), pp. 438-439. (Intervento presentato al convegno XX International Congress on Anti-Cancer Treatments ICACT tenutosi a Paris-France nel 3-6 Febbraio 2009).
Preliminary results on toxicology and mutagenic effects of buckypaper (BP) of multiwalled carbon nanotubes (MWCNTs) on metabolism and immunological modification in vivo and in vitro
CHIARETTI, Massimo;CUCINA, Alessandra;DI SOTTO, ANTONELLA;MAZZANTI, Gabriela;BOSCO, Sandro;CARRU, Giovanna Angela;MASCIANGELO, Raffaele;DE BELLIS, GIOVANNI;FAIOLA, Fabio;NICOLETTI, CARMINE;
2009
Abstract
Preliminary results on toxicology and mutagenic effects of buckypaper (BP) of multiwalled carbon nanotubes (MWCNTs) on metabolism and immunological modification in vivo and in vitroI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.