Thyroglobulin (Tg) levels were found to be elevated in 30 of 35 patients with euthyroid sporadic goiter and in 15 of 37 patients with euthyroid endemic goiter. The elevated Tg levels in the goitrous patients did not correlate with either goiter size. TSH levels, or urinary iodine excretion, but did correlate with the triiodothyronine to thyroxine ratio. It was concluded, therefore, that in both sporadic and endemic euthyroid goiters, factors other than goiter size and TSH, such as hypoiodination of Tg may be responsible for the elevated Tg secretion.
Increased serum thyroglobulin levels in patients with nontoxic goiter / V., Pezzino; R., Vigneri; S., Squatrito; Filetti, Sebastiano; M., Camus; P., Polosa. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. - ISSN 0021-972X. - STAMPA. - 46:4(1978), pp. 653-657. [10.1210/jcem-46-4-653]
Increased serum thyroglobulin levels in patients with nontoxic goiter
FILETTI, SEBASTIANO;
1978
Abstract
Thyroglobulin (Tg) levels were found to be elevated in 30 of 35 patients with euthyroid sporadic goiter and in 15 of 37 patients with euthyroid endemic goiter. The elevated Tg levels in the goitrous patients did not correlate with either goiter size. TSH levels, or urinary iodine excretion, but did correlate with the triiodothyronine to thyroxine ratio. It was concluded, therefore, that in both sporadic and endemic euthyroid goiters, factors other than goiter size and TSH, such as hypoiodination of Tg may be responsible for the elevated Tg secretion.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.