An X;9;22 translocation was detected in bone marrow cells of a female patient with blastic crisis of CML. A dynamic study following 5-BrdU treatment showed that the inactive late-replicating X chromosome was the normal one. This pattern of X-chromosome replication appears to be superimposable on the most usual model found in congenital X/autosome translocations. It is suggested that preferential autosome translocation onto the active X chromosome could be the general rule in acquired X/autosome translocations associated with long survival.

Inactive normal X in a female leukemic patient with an acquired X/autosome translocation / Dallapiccola, B; Alimena, Giuliana. - In: HUMAN GENETICS. - ISSN 0340-6717. - 48:(1979), pp. 169-177.

Inactive normal X in a female leukemic patient with an acquired X/autosome translocation.

ALIMENA, Giuliana
1979

Abstract

An X;9;22 translocation was detected in bone marrow cells of a female patient with blastic crisis of CML. A dynamic study following 5-BrdU treatment showed that the inactive late-replicating X chromosome was the normal one. This pattern of X-chromosome replication appears to be superimposable on the most usual model found in congenital X/autosome translocations. It is suggested that preferential autosome translocation onto the active X chromosome could be the general rule in acquired X/autosome translocations associated with long survival.
1979
01 Pubblicazione su rivista::01a Articolo in rivista
Inactive normal X in a female leukemic patient with an acquired X/autosome translocation / Dallapiccola, B; Alimena, Giuliana. - In: HUMAN GENETICS. - ISSN 0340-6717. - 48:(1979), pp. 169-177.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/411076
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