Eighty-nine patients who developed a secondary hematologic disorder and were studied with chromosome analysis were collected from nine institutions. The results of the study confirmed previous findings, in particular, -5/5q-, -7/7q-, -17, and +21 were the most frequently encountered aberrations. Moreover, a t(1;7)(p11;p11) was reported in four cases and consistent chromosome abnormalities were observed in a small group of patients who had been treated only with surgery, but not with chemo- or radiotherapy for a previous tumor.
Cytogenetic analyses in 89 patiens with secondary hematologic disorders. Results of a cooperative study / Zaccaria, A., Alimena, G., Baccarani, M., Billstrom, R., Carbonell, F., Castoldi, G.l., Fuscaldo, K., Hecht, F., Hossfeld, D.k., Mitelman, F., Rosti, G., Sandberg, A.a., Tassinari, A., Testoni, N., Tura, S.. - In: CANCER GENETICS AND CYTOGENETICS. - ISSN 0165-4608. - 26:(1987), pp. 65-74. [10.1016/0165-4608(87)90134-8]
Cytogenetic analyses in 89 patiens with secondary hematologic disorders. Results of a cooperative study.
ALIMENA, Giuliana;
1987
Abstract
Eighty-nine patients who developed a secondary hematologic disorder and were studied with chromosome analysis were collected from nine institutions. The results of the study confirmed previous findings, in particular, -5/5q-, -7/7q-, -17, and +21 were the most frequently encountered aberrations. Moreover, a t(1;7)(p11;p11) was reported in four cases and consistent chromosome abnormalities were observed in a small group of patients who had been treated only with surgery, but not with chemo- or radiotherapy for a previous tumor.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
