Tetraploid karyotypes without structural chromosome abnormalities were found in approximately 50% of the bone marrow cells in two patients with acute lymphoblastic leukemia with L2 morphology and 'null cell' immunophenotype. Strict tetraploidy (4n = 92) has not been reported as the sole karyotypic rearrangement in bone marrow neoplasia, but may represent a previously unrecognized cytogenetic leukemia subtype.

Tetraploid karyotype (92,XXYY) in two patients with acute lymphoblastic leukemia / Sverre, Heim; Alimena, Giuliana; Rolf, Billstrom; Daniela, Diverio; Ulf, Kristoffersson; Mandhal, ; Mauro, Nanni; Felix, Mitelman. - In: CANCER GENETICS AND CYTOGENETICS. - ISSN 0165-4608. - 29:1(1987), pp. 129-133. [10.1016/0165-4608(87)90039-2]

Tetraploid karyotype (92,XXYY) in two patients with acute lymphoblastic leukemia

ALIMENA, Giuliana;
1987

Abstract

Tetraploid karyotypes without structural chromosome abnormalities were found in approximately 50% of the bone marrow cells in two patients with acute lymphoblastic leukemia with L2 morphology and 'null cell' immunophenotype. Strict tetraploidy (4n = 92) has not been reported as the sole karyotypic rearrangement in bone marrow neoplasia, but may represent a previously unrecognized cytogenetic leukemia subtype.
1987
01 Pubblicazione su rivista::01a Articolo in rivista
Tetraploid karyotype (92,XXYY) in two patients with acute lymphoblastic leukemia / Sverre, Heim; Alimena, Giuliana; Rolf, Billstrom; Daniela, Diverio; Ulf, Kristoffersson; Mandhal, ; Mauro, Nanni; Felix, Mitelman. - In: CANCER GENETICS AND CYTOGENETICS. - ISSN 0165-4608. - 29:1(1987), pp. 129-133. [10.1016/0165-4608(87)90039-2]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/409337
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