CSF from a patient with congenital indifference to pain was found to produce analgesia in the rat following intracerebroventricular injections. The analgesic effect was attenuated by pretreatment with naloxone suggesting the involvement of hyperactive endogenous opiate mechanisms in this patient.
Intracerebroventricular injection of cerebrospinal fluid (CSF) from a patient with congenital indifference to pain induces analgesia in rats / A., Fabbri; F., Fraioli; Cruccu, Giorgio; Manfredi, Mario; C. B., Pert; A., Pert. - In: EXPERIENTIA. - ISSN 0014-4754. - 40:12(1984), pp. 1365-1366.
Intracerebroventricular injection of cerebrospinal fluid (CSF) from a patient with congenital indifference to pain induces analgesia in rats.
CRUCCU, Giorgio;MANFREDI, Mario;
1984
Abstract
CSF from a patient with congenital indifference to pain was found to produce analgesia in the rat following intracerebroventricular injections. The analgesic effect was attenuated by pretreatment with naloxone suggesting the involvement of hyperactive endogenous opiate mechanisms in this patient.File allegati a questo prodotto
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